The ports file can be used to specify multiple source and destination pairs. They can be lids or guids. If guids, use the -G option to indicate that.
Generically:
# comment <src> <dst>
Example:
73 207 203 657 531 101 > OR < 0x0008f104003f125c 0x0008f104003f133d 0x0008f1040011ab07 0x0008f104004265c0 0x0008f104007c5510 0x0008f1040099bb08