PYTHON setup.py build_ext --inplace PYTHON -c "import a" ######## setup.py ######## from Cython.Build import cythonize from distutils.core import setup # Add ./site-packages to sys.path from os.path import realpath import sys sys.path.append(realpath('site-packages')) setup( ext_modules = cythonize("*.pyx"), ) ######## site-packages/b/__init__.py ######## ######## site-packages/b/other.pxd ######## cdef extern from "foo.c": int foo(int) ######## site-packages/b/foo.c ######## static int foo(int a) { return a * a; } ######## a.pyx ######## from b.other cimport foo print foo(10) cimport b.other print b.other.foo(10)