diff --git a/cryptsetup.spec b/cryptsetup.spec
index 2bc02d4..0d2ea1a 100644
--- a/cryptsetup.spec
+++ b/cryptsetup.spec
@@ -152,6 +152,9 @@ make %{?_smp_mflags}
 %if %{python3_enable}
 pushd %{py3dir}
 %configure --enable-python --with-python_version=3 --enable-fips --enable-pwquality --enable-libargon2
+# remove rpath
+sed -i 's|^hardcode_libdir_flag_spec=.*|hardcode_libdir_flag_spec=""|g' libtool
+sed -i 's|^runpath_var=LD_RUN_PATH|runpath_var=DIE_RPATH_DIE|g' libtool
 make %{?_smp_mflags}
 popd
 %endif